Aplastic Anemia and PNH Treatment Centers in Alabama
Finding experienced care is especially important for people diagnosed with aplastic anemia, paroxysmal nocturnal hemoglobinuria (PNH), or an aplastic anemia and PNH overlap diagnosis. These rare blood disorders may require treatment from hematologists familiar with bone marrow failure, immunosuppressive therapy, complement inhibitor medications, blood transfusion support, and bone marrow or stem cell transplantation.
This directory connects Alabama patients and families with specialized treatment programs, regional hematology clinics, pediatric services, transplant resources, financial assistance, lodging, and national patient-support organizations.
Important: Not every hematology clinic listed below specializes specifically in aplastic anemia or PNH. Contact the clinic before scheduling to confirm whether its physicians treat your condition. Patients with severe, complicated, or uncertain diagnoses may need evaluation at an academic medical center or specialized bone marrow failure program.
Specialized Adult Care in Alabama
UAB Hematology and Oncology
Location:
The Kirklin Clinic of UAB Hospital
2000 6th Avenue South, Floor 5
Birmingham, AL 35233
Phone: 205-801-9034
UAB Medicine is one of Alabama’s primary academic referral centers for patients with complicated blood disorders. Its hematology program includes physicians who evaluate anemia, bone marrow disorders, blood-cell abnormalities, and conditions that may require advanced treatment or transplantation.
Services may include:
- Diagnostic evaluation of anemia and abnormal blood counts
- Bone marrow testing
- Management of nonmalignant blood disorders
- Immunosuppressive treatment
- Blood transfusion support
- Medication management
- Second-opinion consultations
- Referral for blood or marrow transplantation
- Clinical research and clinical trials
Find a UAB hematology provider
View UAB providers specializing in anemia and bone marrow disorders
Visit the UAB Medicine website
UAB Blood and Marrow Transplantation and Cellular Therapy Program
Location:
The Kirklin Clinic of UAB Hospital
2000 6th Avenue South, Floor 5
Birmingham, AL 35233
Phone: 205-975-2236
The UAB Blood and Marrow Transplantation and Cellular Therapy Program provides adult transplant evaluation and treatment. A hematopoietic stem cell transplant may be considered for certain patients with severe aplastic anemia, depending on age, overall health, disease severity, donor availability, previous treatments, and other medical factors.
The program provides:
- Allogeneic stem cell transplantation
- Autologous stem cell transplantation
- Related-donor transplantation
- Unrelated-donor transplantation
- Haploidentical transplantation
- Umbilical cord blood transplantation when appropriate
- Donor-search coordination
- Pre-transplant evaluation
- Inpatient transplant care
- Long-term follow-up and survivorship services
Learn about UAB’s Blood and Marrow Transplantation and Cellular Therapy Program
Find UAB bone marrow transplant providers
Pediatric Aplastic Anemia and Bone Marrow Failure Care
Children’s of Alabama Bone Marrow Failure Program
Location:
Children’s of Alabama
1600 7th Avenue South
Birmingham, AL 35233
Hematology and Oncology Nurse Line: 205-638-9285
The Bone Marrow Failure Program at Children’s of Alabama provides specialized care for infants, children, teenagers, and young adults with bone marrow failure syndromes.
The care team may include physicians, nurses, nurse practitioners, social workers, child-life specialists, neuropsychologists, school liaisons, and other pediatric professionals.
Services may include:
- Evaluation of acquired and inherited bone marrow failure
- Pediatric aplastic anemia care
- Diagnostic bone marrow testing
- Medical and immunosuppressive therapies
- Blood and platelet transfusion support
- Infection monitoring
- Genetic evaluation when appropriate
- Bone marrow transplant evaluation
- Family education and psychosocial support
- School-support and child-life services
A physician referral is generally required for a first appointment in the Pediatric Hematology-Oncology Clinic.
Learn about the Children’s of Alabama Bone Marrow Failure Program
Visit the Alabama Center for Childhood Cancer and Blood Disorders
Children’s of Alabama Blood and Marrow Transplantation Program
Location:
Children’s of Alabama
1600 7th Avenue South
Birmingham, AL 35233
The Blood and Marrow Transplantation Program at Children’s of Alabama is the state’s dedicated pediatric bone marrow transplant program. It treats children with bone marrow failure syndromes, immune deficiencies, rare genetic conditions, blood disorders, and certain cancers.
Services may include:
- Pediatric bone marrow transplant evaluation
- Related and unrelated donor transplantation
- Donor matching and transplant preparation
- Inpatient transplant care
- Infection prevention and monitoring
- Family support during treatment
- Long-term follow-up after transplant
Learn about pediatric bone marrow transplantation at Children’s of Alabama
Regional Hematology Clinics
Regional hematology clinics may help patients receive blood tests, transfusions, infusions, medication monitoring, and follow-up care closer to home. Patients with aplastic anemia or PNH should confirm that a clinic has experience treating rare, nonmalignant blood disorders.
A local hematologist may also coordinate care with UAB, Children’s of Alabama, the National Institutes of Health, or another specialized bone marrow failure center.
Hematology and Oncology Associates of Alabama
Location:
513 Brookwood Boulevard, Suite 275
Birmingham, AL 35209
Phone: 205-502-4700
Hematology and Oncology Associates of Alabama provides adult hematology and medical oncology services in the Birmingham area.
Potentially relevant services include:
- Hematology consultations
- Blood-count monitoring
- Evaluation of anemia and other blood disorders
- Infusion therapy
- Medication management
- Transfusion coordination
- Laboratory services
- Patient education and financial counseling
Visit Hematology and Oncology Associates of Alabama
HOAA Gadsden Cancer Clinic
Location:
705 Goodyear Avenue
Gadsden, AL 35903
Phone: 256-492-0375
HOAA Gadsden provides community-based hematology and blood-disorder care for patients in northeastern Alabama.
Potentially relevant services include:
- Hematology consultations
- Blood-disorder evaluation
- Infusion treatment
- Laboratory testing
- Blood-count monitoring
- Coordination with larger specialty and transplant centers
Visit HOAA Gadsden Cancer Clinic
Clearview Cancer Institute
Main Contact Number: 888-374-1015
Clearview Cancer Institute operates hematology and oncology clinics throughout northern Alabama. Its physicians treat patients with blood disorders and can provide local laboratory work, infusion services, supportive care, and coordination with specialty centers.
Alabama locations include:
- Anniston
- Athens
- Cullman
- Decatur
- Florence
- Huntsville
- Jasper
- Madison
- Muscle Shoals
- Scottsboro
Available services vary by location and may include:
- Hematology consultations
- Blood-disorder management
- Infusion therapy
- Laboratory services
- Genetic counseling
- Social-work services
- Financial counseling
- Clinical-trial screening
- Coordination with academic medical centers
View all Clearview Cancer Institute locations
Find a Clearview hematology or oncology physician
Visit Clearview Cancer Institute
USA Health Mitchell Cancer Institute
Location:
1660 Spring Hill Avenue
Mobile, AL 36604
Phone: 251-665-8000
USA Health Mitchell Cancer Institute provides hematology and medical oncology services for patients in Mobile and southern Alabama. Its hematologists evaluate malignant and nonmalignant blood disorders, including chronic anemia and abnormal blood-cell counts.
Potentially relevant services include:
- Hematology consultations
- Evaluation of chronic anemia
- Blood-disorder management
- Laboratory testing
- Infusion services
- Medication treatment
- Support services
- Coordination with specialty and transplant programs
Learn about USA Health hematology services
Visit the Mitchell Cancer Institute
USA Health Mitchell Cancer Institute – Fairhope
Location:
1047 Fairhope Avenue
Fairhope, AL 36532
Phone: 251-990-1850
The Fairhope location provides hematology and oncology services for patients in Baldwin County and nearby communities. Call before scheduling to confirm the availability of care for aplastic anemia, PNH, or another nonmalignant blood disorder.
View USA Health medical oncology and hematology services
Infirmary Health Hematology and Oncology
Service Area: Mobile and southern Alabama
Infirmary Health provides hematology and oncology services for patients with cancer and blood disorders in the Mobile area.
Potentially relevant services include:
- Blood-disorder evaluation
- Hematology consultations
- Laboratory monitoring
- Infusion services
- Medication management
- Referral to specialized centers when needed
Learn about Infirmary Health hematology and oncology services
Dothan Hematology and Oncology
Location:
101 Westside Drive
Dothan, AL 36303
Phone: 334-792-9500
Dothan Hematology and Oncology provides care for anemia, bleeding and clotting disorders, abnormal blood counts, leukemia, lymphoma, myeloma, and other blood conditions. The practice also reports offering an on-site bone marrow clinic.
Potentially relevant services include:
- Hematology consultations
- Anemia evaluation
- Bone marrow clinic
- Blood-count monitoring
- Infusion therapy
- Medication treatment
- Laboratory services
- In-house pharmacy services
Learn about Dothan Hematology and Oncology’s hematology services
Visit Dothan Hematology and Oncology
Southeast Health Hematology and Oncology
Location: Dothan, Alabama
Southeast Health provides coordinated hematology and oncology services for patients in southeastern Alabama.
Patients should contact the program directly to ask whether its hematologists treat aplastic anemia, PNH, bone marrow failure, or other nonmalignant blood disorders.
Visit Southeast Health Hematology and Oncology
Alabama Oncology
Service Area: Birmingham and central Alabama
Alabama Oncology operates multiple clinics offering hematology, laboratory testing, infusion treatment, clinical-trial screening, and patient-support services.
Before making an appointment, ask whether a physician at the selected location has experience treating aplastic anemia, PNH, or nonmalignant bone marrow disorders.
Alabama Cancer Care
Service Area: Multiple Alabama communities
Alabama Cancer Care operates regional oncology and hematology locations across the state. Services and physician specialties vary by location.
Patients should confirm whether the nearest clinic evaluates nonmalignant blood disorders and whether it can coordinate treatment with an academic bone marrow failure center.
Find an Alabama Cancer Care location
Getting a Second Opinion
Because aplastic anemia and PNH are rare, patients may benefit from a second opinion when:
- The diagnosis is uncertain
- Blood counts continue to decline
- Severe or very severe aplastic anemia is suspected
- A PNH clone is identified
- Both aplastic anemia and PNH are present
- Immunosuppressive therapy is being considered
- Complement inhibitor therapy is being considered
- A stem cell transplant is being considered
- The current treatment is not working
- New or worsening symptoms develop
- The patient or family wants confirmation of the treatment plan
A second opinion does not necessarily require changing physicians. A specialty center may review test results and make recommendations while the patient continues routine treatment closer to home.
What to Ask Before Scheduling
When contacting a center or hematology clinic, consider asking:
- Does the physician regularly treat aplastic anemia?
- Does the physician regularly treat PNH?
- Does the physician treat patients with both aplastic anemia and a PNH clone?
- Does the clinic manage nonmalignant bone marrow failure disorders?
- Does the clinic provide complement inhibitor infusions or coordinate them locally?
- Can the clinic provide blood and platelet transfusions?
- Does the clinic coordinate with UAB, Children’s of Alabama, NIH, or another specialty center?
- Is a physician referral required?
- Does the clinic accept my insurance?
- Are telehealth appointments available?
- What medical records should I provide before the appointment?
- Is financial counseling or patient navigation available?
Records to Gather for an Appointment
The specialty center may request:
- Complete blood-count results
- Reticulocyte counts
- Bone marrow biopsy and aspiration reports
- Bone marrow pathology slides
- Flow-cytometry results
- PNH clone testing results
- Cytogenetic or genetic testing
- HLA typing
- Transfusion records
- Medication history
- Hospital discharge summaries
- Infection history
- Insurance information
- A list of current symptoms and questions
Ask the receiving center whether it wants actual pathology slides, imaging, laboratory files, or only written reports.
National Aplastic Anemia and PNH Resources
Aplastic Anemia and MDS International Foundation
The Aplastic Anemia and MDS International Foundation provides education and support for people affected by aplastic anemia, PNH, myelodysplastic syndromes, and related bone marrow failure diseases.
Resources include:
- Patient education
- Educational webinars
- Peer support
- Support groups
- Treatment information
- Clinical-trial information
- Patient and caregiver conferences
- PNH educational materials
- Travel assistance for eligible PNH patients
- A patient helpline
Helpline: 800-747-2820, extension 2
Visit the Aplastic Anemia and MDS International Foundation
Access the PNH Patient Toolkit
Learn about the PNH Patient Travel Assistance Fund
View additional patient-support resources
National Marrow Donor Program
The National Marrow Donor Program, formerly widely known as Be The Match, supports patients who may need a blood or marrow transplant.
Resources include:
- Donor-search information
- Transplant education
- One-on-one patient navigation
- Financial-assistance information
- Peer support
- Caregiver resources
- Help preparing for transplant
- Support before and after transplantation
Visit the NMDP Patient Support Center
Explore transplant financial assistance
View helpful transplant organizations
BMT InfoNet
BMT InfoNet provides education and support for patients undergoing bone marrow or stem cell transplantation and cellular therapy.
Resources include:
- Transplant education
- Caregiver information
- Survivorship guidance
- Peer support
- Webinars
- Financial assistance for eligible patients
- Information about transplant complications and recovery
Learn about the Susan K. Stewart Patient Assistance Fund
National Institutes of Health Clinical Center
The National Institutes of Health in Bethesda, Maryland, conducts research and clinical studies involving aplastic anemia, PNH, bone marrow failure, immune-based treatments, and stem cell transplantation.
Patients may need to travel outside Alabama to participate in an NIH evaluation or clinical study. Eligibility depends on the study’s requirements.
Search NIH Clinical Center studies
Learn about aplastic anemia from the National Heart, Lung, and Blood Institute
ClinicalTrials.gov
ClinicalTrials.gov is the federal database of publicly and privately supported clinical studies.
Patients can search for studies involving:
- Aplastic anemia
- Severe aplastic anemia
- PNH
- Bone marrow failure
- Complement inhibitors
- Immunosuppressive therapies
- Stem cell transplantation
- New medications
Search ClinicalTrials.gov for aplastic anemia studies
Search ClinicalTrials.gov for PNH studies
Always discuss a clinical trial with a qualified hematologist before making treatment decisions.
National Organization for Rare Disorders
The National Organization for Rare Disorders provides rare-disease education, advocacy, patient-assistance information, and links to support organizations.
Visit the National Organization for Rare Disorders
Genetic and Rare Diseases Information Center
The Genetic and Rare Diseases Information Center is a federal resource that provides information about rare diseases, research, diagnosis, and patient organizations.
Visit the Genetic and Rare Diseases Information Center
Financial and Insurance Assistance
Alabama Medicaid
Alabama Medicaid provides health coverage to eligible Alabama residents. Patients and families can use the Medicaid website to review eligibility information, apply for coverage, update account information, and locate contact information.
Recipient Call Center: 800-362-1504
View Alabama Medicaid contact information
Social Security Disability Benefits
Some patients who are unable to work because of severe aplastic anemia, PNH, complications, or treatment may be eligible for Social Security Disability Insurance or Supplemental Security Income.
Eligibility is based on medical evidence, work history, income, functional limitations, and other program requirements.
Learn about Social Security disability benefits
Hospital Financial Counselors and Social Workers
Ask your treatment center for assistance from a:
- Financial counselor
- Oncology social worker
- Transplant social worker
- Patient navigator
- Insurance authorization specialist
- Medication-assistance coordinator
These professionals may help with:
- Insurance approvals
- Medication copays
- Transportation
- Temporary lodging
- Food assistance
- Disability paperwork
- Family and Medical Leave Act paperwork
- Pharmaceutical assistance programs
- Charity-care applications
- Transplant-related grants
Alabama Community Assistance
211 Connects Alabama
Alabama residents can dial 211 for help locating local health and human-service programs.
Assistance may be available for:
- Food
- Housing
- Utility bills
- Transportation
- Health services
- Prescription expenses
- Caregiver support
- Disability services
- Mental-health services
- Emergency assistance
Phone: Dial 211
Lodging for Families Receiving Treatment
Ronald McDonald House Charities of Alabama
Location:
1700 4th Avenue South
Birmingham, AL 35233
Phone: 205-638-7255
Ronald McDonald House Charities of Alabama provides temporary accommodations and support for eligible families whose children are receiving medical care in Birmingham.
Families should ask their child’s hospital social worker or care team about eligibility and the referral process.
Visit Ronald McDonald House Charities of Alabama
Review lodging information for Children’s of Alabama families
Medication and Copay Assistance
Some manufacturers of PNH medications and other specialty treatments offer patient-support programs. Assistance may include:
- Insurance-benefit verification
- Prior-authorization support
- Copay assistance for eligible patients
- Patient-assistance programs for eligible uninsured or underinsured patients
- Infusion coordination
- Nurse support
- Medication education
Eligibility and program terms can change. Patients should speak with their physician, specialty pharmacy, hospital financial counselor, or medication manufacturer before enrolling.
Independent assistance may also be available through:
Patient Access Network Foundation
Availability depends on diagnosis, insurance status, household income, and whether a disease-specific fund is open.
Support for Caregivers and Families
Aplastic anemia and PNH can affect the entire family. Caregivers may need help managing appointments, medications, travel, insurance, work responsibilities, and emotional stress.
Helpful forms of support may include:
- Patient and caregiver support groups
- Peer mentoring
- Family counseling
- Hospital social-work services
- Child-life services
- School coordination
- Transportation assistance
- Temporary lodging
- Meal assistance
- Respite care
- Workplace-leave assistance
- Mental-health support
Patients and caregivers can ask their hospital social worker or the AAMDSIF Helpline for help locating appropriate services.
When to Seek Immediate Medical Care
Follow the emergency instructions provided by your hematologist. Seek urgent medical attention for symptoms such as:
- A fever at or above the threshold established by your treatment team
- Uncontrolled or unusual bleeding
- Blood in the urine or stool
- Black, tarry stools
- Severe headache
- New confusion
- Sudden weakness or numbness
- Difficulty breathing
- Chest pain
- Fainting
- Rapidly worsening fatigue
- New pain, redness, warmth, or swelling in an arm or leg
- Severe abdominal pain
- Signs of a serious infection
- Any symptom your care team has instructed you to treat as an emergency
Do not rely on an online directory during a medical emergency. Call 911 or go to the nearest emergency department.
Help Us Keep This Directory Current
Treatment programs, physician availability, clinic locations, phone numbers, and patient-assistance programs may change.
If you represent an Alabama treatment center or know of an aplastic anemia or PNH resource that should be added, please contact PNHAA.
Please include:
- Organization or treatment-center name
- City and state
- Website
- Phone number
- Services provided
- Whether the center treats adults, children, or both
- Whether the center specifically treats aplastic anemia, PNH, or bone marrow failure
Medical Disclaimer
This directory is provided for general educational and informational purposes only. It is not medical advice and should not be used to diagnose a condition, select a treatment, or replace guidance from a qualified healthcare professional.
Inclusion in this directory does not constitute certification, accreditation, recommendation, or endorsement by PNHAA. Patients should independently confirm each provider’s credentials, experience, insurance participation, referral requirements, and ability to treat aplastic anemia or PNH.
Always consult your hematologist or medical team before beginning, changing, or stopping treatment.